• (4) (PDF) Rheumatoid arthritis, Klippel-Feil syndrome and Pott’s disease in Cardinal Carlo de' Medici (1595-1666) | Antonio Fornaciari - Academia.edu

    Typ Webseite
    URL https://www.academia.edu/1178266/Rheumatoid_arthritis_Klippel_Feil_syndrome_and_Pott_s_disease_in_Cardinal_Carlo_de_Medici_1595_1666_
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  • (4) (PDF) Split cervical spinal cord with Klippel—Feil syndrome: seven cases | Károly Dávid - Academia.edu

    Typ Webseite
    URL https://www.academia.edu/33080064/Split_cervical_spinal_cord_with_Klippel_Feil_syndrome_seven_cases
    Heruntergeladen am 9.11.2021, 21:23:41
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  • A Potential Case of Klippel-Feil Syndrome at the Kellogg Village Site (22CL527)

    Typ Zeitschriftenartikel
    Autor Lynn Funkhouser
    Zusammenfassung Klippel-Feil Syndrome (KFS) is a rare genetic defect resulting from failure of segmentation in cervical vertebrae. This reporting focuses on the differential diagnosis of a possible case of Klippel-Feil Syndrome in a 30-35 male skeleton from the
    Sprache en
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/27319399/A_Potential_Case_of_Klippel_Feil_Syndrome_at_the_Kellogg_Village_Site_22CL527_
    Heruntergeladen am 9.11.2021, 21:34:58
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  • Atlas der klinischen Syndrome für Klinik und Praxis

    Typ Buch
    Herausgeber Hans-Rudolf Wiedemann
    Herausgeber Jürgen Kunze
    Herausgeber Jürgen Spanger
    Herausgeber Jürgen Spranger
    Datum 2001
    Sprache ger
    Bibliothekskatalog K10plus ISBN
    URL https://www.livivo.de/doc/496467
    Ort Stuttgart
    Verlag Schattauer
    ISBN 978-3-7945-2043-5
    Auflage 5., völlig überarb. und erw. Aufl
    Anzahl der Seiten 878
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  • Can shark eggs clarify how human necks develop?

    Typ Blog-Post
    Zusammenfassung A new look at the fused neck vertebrae of elephant sharks could help researchers better understand how neck development can go awry in humans.
    Datum 2015-10-21T11:29:59-04:00
    Sprache en-US
    URL https://www.futurity.org/neck-vertebrae-elephant-sharks-1030992-2/
    Heruntergeladen am 8.8.2022, 14:40:33
    Extra Section: Health and Medicine
    Titel des Blogs Futurity
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    Verwandte Einträge

    • Development of the Synarcual in the Elephant Sharks (Holocephali; Chondrichthyes): Implications for Vertebral Formation and Fusion
  • Cervical vertebral malformations in 9 dogs: radiological findings, treatment options and outcomes

    Typ Zeitschriftenartikel
    Autor Ricardo Fernandes
    Autor Noel Fitzpatrick
    Autor Clare Rusbridge
    Autor Jeremy Rose
    Autor Colin J. Driver
    Zusammenfassung Background: Disregarding atlantoaxial instability in toy breed dogs associated with dens malformation and cervical spondylomyelopathy; cervical vertebral malformations are rare and poorly characterised in veterinary medicine and consequently treatment strategies and clinical outcome are sparsely documented. Results: Electronic clinical records at our veterinary referral hospital between April 2009 and November 2018 were searched for patients presented with cervical myelopathy secondary to an underlying suspected vertebral malformation/instability. Nine dogs met the inclusion criteria. Two dogs were diagnosed with atlantoaxial pseudoarthrosis, two dogs with a syndrome similar to Klippel-Feil in humans, two dogs with congenital cervical fusion, two dogs with congenital C2-C3 canal stenosis and deficiencies of the dorsal arch of the atlas and laminae of the axis and one with axial rotatory displacement. Tetraparesis, proprioceptive deficits, cervical hyperesthesia and cervical scoliosis were the most common clinical signs. The axis was the most commonly affected vertebrae (8/9 patients). Patients diagnosed with Klippel-Feil-like Syndrome were the younger (average of 262.5 days) and patients diagnosed with fused vertebrae the oldest (average of 2896 days) in our studied population (average of 1580.8 days). Conclusion: Cervical vertebral malformations are rare, or alternatively, being underdiagnosed in veterinary medicine. Patients diagnosed with Klippel-Feil-like Syndrome had a successful medium and long-term outcome with conservative management. Surgical treatment was often indicated for the other conditions presented in this study due to spinal instability and/or myelopathy. Stabilisations via ventral approaches were revealed to be safe. Multicentre and prospective studies are necessary in veterinary medicine to better characterise clinical outcomes in cervical vertebral malformations.
    Datum 12/2019
    Sprache en
    Kurztitel Cervical vertebral malformations in 9 dogs
    Bibliothekskatalog DOI.org (Crossref)
    URL https://irishvetjournal.biomedcentral.com/articles/10.1186/s13620-019-0141-9
    Heruntergeladen am 2.7.2022, 16:27:29
    Band 72
    Seiten 2
    Publikation Irish Veterinary Journal
    DOI 10.1186/s13620-019-0141-9
    Ausgabe 1
    Zeitschriften-Abkürzung Ir Vet J
    ISSN 2046-0481
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  • Cervico-Oculo-Acusticus (Wildervanck's) syndrome: a clinical variant of Klippel-Feil sequence?

    Typ Zeitschriftenartikel
    Autor G. Corsello
    Autor A. Carcione
    Autor L. Castro
    Autor L. Giuffrè
    Datum 1990/05
    Sprache en
    Kurztitel Cervico-Oculo-Acusticus (Wildervanck's) syndrome
    Bibliothekskatalog www.thieme-connect.com
    URL http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-1025514
    Heruntergeladen am 27.7.2022, 16:36:53
    Rechte © Georg Thieme Verlag KG Stuttgart · New York
    Extra Publisher: © Georg Thieme Verlag KG Stuttgart · New York
    Band 202
    Seiten 176-179
    Publikation Klinische Pädiatrie
    DOI 10.1055/s-2007-1025514
    Ausgabe 3
    Zeitschriften-Abkürzung Klin Padiatr
    ISSN 0300-8630, 1439-3824
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  • Congenital Diseases and Syndromes

    Typ Buch
    Herausgeber Jarrah Ali Al-Tubaikh
    Herausgeber Maximilian F. Reiser
    Datum 2009
    Sprache en
    Bibliothekskatalog DOI.org (Crossref)
    URL http://link.springer.com/10.1007/978-3-642-00160-4
    Heruntergeladen am 26.7.2022, 16:38:06
    Extra DOI: 10.1007/978-3-642-00160-4
    Ort Berlin, Heidelberg
    Verlag Springer Berlin Heidelberg
    ISBN 978-3-642-00159-8 978-3-642-00160-4
    Hinzugefügt am 26.7.2022, 16:38:06
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  • Development of the Synarcual in the Elephant Sharks (Holocephali; Chondrichthyes): Implications for Vertebral Formation and Fusion

    Typ Zeitschriftenartikel
    Autor Zerina Johanson
    Autor Catherine Boisvert
    Autor Anton Maksimenko
    Autor Peter Currie
    Autor Kate Trinajstic
    Zusammenfassung The synarcual is a structure incorporating multiple elements of two or more anterior vertebrae of the axial skeleton, forming immediately posterior to the cranium. It has been convergently acquired in the fossil group ‘Placodermi’, in Chondrichthyes (Holocephali, Batoidea), within the teleost group Syngnathiformes, and to varying degrees in a range of mammalian taxa. In addition, cervical vertebral fusion presents as an abnormal pathology in a variety of human disorders. Vertebrae develop from axially arranged somites, so that fusion could result from a failure of somite segmentation early in development, or from later heterotopic development of intervertebral bone or cartilage. Examination of early developmental stages indicates that in the Batoidea and the ‘Placodermi’, individual vertebrae developed normally and only later become incorporated into the synarcual, implying regular somite segmentation and vertebral development. Here we show that in the holocephalan Callorhinchus milii, uniform and regular vertebral segmentation also occurs, with anterior individual vertebra developing separately with subsequent fusion into a synarcual. Vertebral elements forming directly behind the synarcual continue to be incorporated into the synarcual through growth. This appears to be a common pattern through the Vertebrata. Research into human disorders, presenting as cervical fusion at birth, focuses on gene misexpression studies in humans and other mammals such as the mouse. However, in chondrichthyans, vertebral fusion represents the normal morphology, moreover, taxa such Leucoraja (Batoidea) and Callorhinchus (Holocephali) are increasingly used as laboratory animals, and the Callorhinchus genome has been sequenced and is available for study. Our observations on synarcual development in three major groups of early jawed vertebrates indicate that fusion involves heterotopic cartilage and perichondral bone/mineralised cartilage developing outside the regular skeleton. We suggest that chondrichthyans have potential as ideal extant models for identifying the genes involved in these processes, for application to human skeletal heterotopic disorders.
    Datum 04.09.2015
    Sprache en
    Kurztitel Development of the Synarcual in the Elephant Sharks (Holocephali; Chondrichthyes)
    Bibliothekskatalog PLoS Journals
    URL https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135138
    Heruntergeladen am 8.8.2022, 14:50:34
    Extra Publisher: Public Library of Science
    Band 10
    Seiten e0135138
    Publikation PLOS ONE
    DOI 10.1371/journal.pone.0135138
    Ausgabe 9
    Zeitschriften-Abkürzung PLOS ONE
    ISSN 1932-6203
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    Verwandte Einträge

    • Can shark eggs clarify how human necks develop?
  • Diagnosing a possible case of juvenile idiopathic arthritis: A palaeopathology study from the Ishkeenickh River Cave Site

    Typ Zeitschriftenartikel
    Autor Marla MacKinnon
    Zusammenfassung In the summer of 1967, a relatively complete skeleton of a juvenile was excavated from the Ishkeenickh River Cave Site (now the Ksi Hlginx River) in British Columbia, Canada, dating from approximately 2000 years ago. This individual, likely aged
    Datum 2016
    Sprache en
    Kurztitel Diagnosing a possible case of juvenile idiopathic arthritis
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/34516746/Diagnosing_a_possible_case_of_juvenile_idiopathic_arthritis_A_palaeopathology_study_from_the_Ishkeenickh_River_Cave_Site
    Heruntergeladen am 10.8.2022, 11:46:43
    Band 15
    Seiten 69
    Publikation International Journal of Paleopathology
    ISSN 1879-9817
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  • Halswirbelsäule (HWS) - Anatomie

    Typ Webseite
    Zusammenfassung Die Halswirbelsäule (HWS) besteht aus 7 Halswirbeln. Lies hier alles über Atlas, Axis, Bänder, Gelenke, Entwicklung, HWS-Syndrom und mehr!
    Sprache de
    URL https://www.kenhub.com/de/library/anatomie/halswirbelsaule-hws
    Heruntergeladen am 29.7.2022, 12:55:48
    Titel der Website Kenhub
    Hinzugefügt am 29.7.2022, 12:55:48
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  • Klippel-Feil Syndrome with Sprengel Deformity

    Typ Zeitschriftenartikel
    Autor Violeta V Groudeva
    Autor Georgi P Georgiev
    Zusammenfassung Coexistence of Klippel-Feil syndrome with Sprengel deformity and omovertebral bone is a rare complex bone abnormality with unknown incidence and etiology. Herein, we report a case of a 6-year-old girl with coexistence of these congenital abnormalities evaluated by three-dimensional computed tomography. We also make a brief review and discuss in details the role of this imaging modality in the evaluation of such complex cases.
    Datum 2019-05-25
    Sprache en
    Bibliothekskatalog DOI.org (Crossref)
    URL http://www.radiologycases.com/index.php/radiologycases/article/view/3565
    Heruntergeladen am 2.7.2022, 15:57:36
    Band 13
    Seiten 24-29
    Publikation Journal of Radiology Case Reports
    DOI 10.3941/jrcr.v13i5.3565
    Ausgabe 5
    Zeitschriften-Abkürzung Radiology Case
    ISSN 1943-0922
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  • Kranker Pharao: Tutanchamun hatte ein krummes Kreuz

    Typ Zeitungsartikel
    Zusammenfassung Wissenschaftler aus Großbritannien und Neuseeland haben im Zuge eines britischen TV-Specials den Gesundheitszustand des sagenumwobenen ägyptischen Königs unter die Lupe genommen. Der junge Mann hatte es nicht leicht.
    Datum 2002-10-01
    Sprache de
    Kurztitel Kranker Pharao
    Bibliothekskatalog www.spiegel.de
    URL https://www.spiegel.de/wissenschaft/natur/kranker-pharao-tutanchamun-hatte-ein-krummes-kreuz-a-216360.html
    Heruntergeladen am 9.11.2021, 21:56:01
    Teil Wissenschaft
    Publikation Der Spiegel
    ISSN 2195-1349
    Hinzugefügt am 9.11.2021, 21:56:01
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    • Wissenschaft
    • Natur
    • Tutanchamun
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  • Monsters and the case of L. Joseph: André Feil's thesis on the origin of the Klippel-Feil syndrome and a social transformation of medicine

    Typ Zeitschriftenartikel
    Autor Evgenii Belykh
    Autor Kashif Malik
    Autor Isabelle Simoneau
    Autor Kaan Yagmurlu
    Autor Ting Lei
    Autor Daniel D. Cavalcanti
    Autor Vadim A. Byvaltsev
    Autor Nicholas Theodore
    Autor Mark C. Preul
    Zusammenfassung André Feil (1884–1955) was a French physician best recognized for his description, coauthored with Maurice Klippel, of patients with congenital fusion of cervical vertebrae, a condition currently known as Klippel-Feil syndrome. However, little is known about his background aside from the fact that he was a student of Klippel and a physician who took a keen interest in describing congenital anomalies. Despite the relative lack of information on Feil, his contributions to the fields of spinal disease and teratology extended far beyond science to play an integral role in changing the misguided perception shrouding patients with disfigurements, defects, deformities, and so-called monstrous births. In particular, Feil's 1919 medical school thesis on cervical abnormalities was a critical publication in defying long-held theory and opinion that human “monstrosities,” anomalies, developmental abnormalities, and altered congenital physicality were a consequence of sinful behavior or a reversion to a primitive state. Indeed, his thesis on a spinal deformity centering on his patient, L. Joseph, was at the vanguard for a new view of a patient as nothing less than fully human, no matter his or her physicality or appearance.
    Datum 2016/07/01
    Sprache en_US
    Kurztitel Monsters and the case of L. Joseph
    Bibliothekskatalog thejns.org
    URL https://thejns.org/focus/view/journals/neurosurg-focus/41/1/article-pE3.xml
    Heruntergeladen am 9.11.2021, 21:49:41
    Extra Publisher: American Association of Neurological Surgeons Section: Neurosurgical Focus
    Band 41
    Seiten E3
    Publikation Neurosurgical Focus
    DOI 10.3171/2016.3.FOCUS15488
    Ausgabe 1
    ISSN 1092-0684
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  • Neolithic individual with possible Klippel-Feil syndrome and his place in the community.

    Typ Zeitschriftenartikel
    Autor Zuzana Hukelova
    Zusammenfassung In this paper, a possible case of Klippel-Feil syndrome (KFS) from Vráble, Slovakia, is presented and discussed as regards the individual’s life within community. KFS is a rare congenital disease, most frequently manifesting as synostosis of the
    Sprache en
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/38499646/Neolithic_individual_with_possible_Klippel_Feil_syndrome_and_his_place_in_the_community
    Heruntergeladen am 9.11.2021, 21:22:51
    Publikation Poster
    Hinzugefügt am 9.11.2021, 21:22:51
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  • Neurologie systematisch

    Typ Buch
    Autor Andreas Schwartz
    Datum 2000
    URL https://www.livivo.de/doc/474126
    Ort Bremen
    Verlag UNI-MED-Verl.
    ISBN 978-3-89599-147-9
    Reihe Klinische Lehrbuchreihe
    Hinzugefügt am 24.2.2022, 17:16:54
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  • Paralysis and severe disability requiring intensive care in Neolithic Asia

    Typ Zeitschriftenartikel
    Autor Marc F. Oxenham
    Autor Lorna Tilley
    Autor Hirofumi Matsumura
    Autor Lan Cuong Nguyen
    Autor Kim Thuy Nguyen
    Autor Kim Dung Nguyen
    Autor Kate Domett
    Autor Damien Huffer
    Zusammenfassung This communication documents one of the earliest verifiable cases of human paralysis associated with severe spinal pathology. A series of skeletal abnormalities is described for a young adult male (M9) from a Southeast Asian Neolithic community. Differential diagnosis suggests that M9 suffered from a severely disabling congenital fusion of the spine (Klippel–Feil Syndrome, Type III), resulting in child-onset lower body paralysis at a minimum (maximally quadriplegia). M9 experienced severe, most probably total, incapacitation for at least a decade prior to death. In the prehistoric context, this individual’s condition would have rendered him completely dependent on others for survival.
    Datum 2009
    Sprache en
    Bibliothekskatalog DOI.org (Crossref)
    URL http://www.jstage.jst.go.jp/article/ase/117/2/117_081114/_article
    Heruntergeladen am 26.7.2022, 16:32:27
    Band 117
    Seiten 107-112
    Publikation Anthropological Science
    DOI 10.1537/ase.081114
    Ausgabe 2
    Zeitschriften-Abkürzung AS
    ISSN 0918-7960, 1348-8570
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    Notizen:

    • Diese Mitteilung dokumentiert einen der frühesten nachweisbaren Fälle menschlicher Lähmung in Verbindung mit einer schweren Pathologie der Wirbelsäule. Es wird eine Reihe von Skelettanomalien bei einem jungen erwachsenen Mann (M9) aus einer südostasiatischen neolithischen Gemeinschaft beschrieben. Die Differentialdiagnose deutet darauf hin, dass M9 an einer schwer behinderten kongenitalen Wirbelsäulenversteifung (Klippel-Feil-Syndrom, Typ III) litt, die mindestens zu einer Lähmung des Unterkörpers im Kindesalter führte (maximal zu einer Tetraplegie). M9 war vor seinem Tod mindestens ein Jahrzehnt lang schwer, wahrscheinlich sogar vollständig, gelähmt. Im prähistorischen Kontext hätte der Zustand dieses Individuums ihn für sein Überleben vollständig von anderen abhängig gemacht.

    Anhänge

    • Oxenham et al. - 2009 - Paralysis and severe disability requiring intensiv.pdf
  • Sacrifice of the Social Outcasts: Two Cases of Klippel-Feil Syndrome at Midnight Terror Cave, Belize

    Typ Zeitschriftenartikel
    Autor C. L. Kieffer
    Zusammenfassung The archaeological record indicates that the ancient Lowland Maya sacrificed a wide variety of people in caves for various reasons. Ritual theorists have proposed that individuals chosen for sacrifice cross-culturally are typically outsiders either
    Datum 2015
    Sprache en
    Kurztitel Sacrifice of the Social Outcasts
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/12033967/Sacrifice_of_the_Social_Outcasts_Two_Cases_of_Klippel_Feil_Syndrome_at_Midnight_Terror_Cave_Belize
    Heruntergeladen am 10.8.2022, 11:29:19
    Band 27
    Seiten n/a-n/a
    Publikation International Journal of Osteoarchaeology
    Ausgabe 1
    ISSN 1047-482X
    Hinzugefügt am 10.8.2022, 11:29:19
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  • Spinal pathology in the Medici family, Grand Dukes of Florence (XVI-XVII centuries)

    Typ Zeitschriftenartikel
    Autor Valentina Giuffra
    Zusammenfassung Spinal pathology in the Medici family, Grand Dukes of Florence (XVI-XVII centuries)
    Sprache en
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/11043577/Spinal_pathology_in_the_Medici_family_Grand_Dukes_of_Florence_XVI_XVII_centuries_
    Heruntergeladen am 9.11.2021, 21:38:24
    Publikation Paleopathology newsletter
    Hinzugefügt am 9.11.2021, 21:38:24
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  • The Klippel-Feil Syndrome: A Case Report

    Typ Zeitschriftenartikel
    Autor Martha Flores
    Zusammenfassung The Klippel-Feil Syndrome: A Case Report
    Sprache en
    Kurztitel The Klippel-Feil Syndrome
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/7390267/The_Klippel_Feil_Syndrome_A_Case_Report
    Heruntergeladen am 9.11.2021, 21:21:40
    Hinzugefügt am 9.11.2021, 21:21:40
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  • The predictive ability of occipital to C3 angle for dysphagia after occipitocervical fusion in patients with combined C2–3 Klippel-Feil syndrome

    Typ Zeitschriftenartikel
    Autor Qiang Zou
    Autor Linnan Wang
    Autor Xi Yang
    Autor Yueming Song
    Autor Limin Liu
    Autor Lei Wang
    Autor Zhongjie Zhou
    Autor Bowen Hu
    Autor Taiyong Chen
    Autor Hao Liu
    Zusammenfassung Background:  Improper occipitocervical alignment after occipitocervical fusion (OCF) may lead to devastating complications, such as dysphagia and/or dyspnea. The occipital to C2 angle (O-C2a), occipital and external acoustic meatus to axis angle (O-EAa) have been used to evaluate occipitospinal alignment. However, it may be difficult to identify the inferior endplate of the C2 vertebra in patients with C2–3 Klippel-Feil syndrome (KFS). The purpose of this study aimed to compare four different parameters for predicting dysphagia after OCF in patients with C2–3 KFS. Methods:  There were 40 patients with C2–3 KFS undergoing OCF between 2010 and 2019. Radiographs of these patients were collected to measure the occipital to C3 angle (O-C3a), O-C2a, occipito-odontoid angle (O-Da), occipital to axial angle (Oc-Axa), and narrowest oropharyngeal airway space (nPAS). The presence of dysphagia was defined as the patient complaining of difficulty or excess endeavor to swallow. Patients were divided into two groups according to whether they had postoperative dysphagia. We evaluated the relationship between each of the angle parameters and nPAS and analyzed their influence to the postoperative dysphagia. Results:  The incidence of dysphagia after OCF was 25% in patients with C2–3 KFS. The Oc-Axa, and nPAS were smaller in the dysphagia group compared to non-dysphagia group at the final follow-up (p < 0.05). Receiver-operating characteristic (ROC) curves showed that dO-C3a had the highest accuracy as a predictor of the dysphagia with an area under the curve (AUC) of 0.868. The differences in O-C3a, O-C2a, O-Da, and Oc-Axa were all linearly correlated with nPAS scores preoperatively and at the final follow-up within C2–3 KFS patients, while there was a higher R­ 2 value between the dO-C3a and dnPAS. Multiple linear regression analysis showed that the difference of O-C3a was the only significant predictor for dnPAS (β = 0.670, p < 0.001). Conclusions:  The change of O-C3a (dO-C3a) is the most reliable indicator for evaluating occipitocervical alignment and predicting postoperative dysphagia in C2–3 KFS patients. Moreover, dO-C3a should be more than − 2° during OCF to reduce the occurrence of postoperative dysphagia.
    Datum 12/2022
    Sprache en
    Bibliothekskatalog DOI.org (Crossref)
    URL https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-022-05072-8
    Heruntergeladen am 2.7.2022, 16:09:08
    Band 23
    Seiten 123
    Publikation BMC Musculoskeletal Disorders
    DOI 10.1186/s12891-022-05072-8
    Ausgabe 1
    Zeitschriften-Abkürzung BMC Musculoskelet Disord
    ISSN 1471-2474
    Hinzugefügt am 2.7.2022, 16:09:08
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  • Unusual neck pathology in a Nevisian prehistoric individual

    Typ Zeitschriftenartikel
    Autor Sonia Zakrzewski
    Zusammenfassung Unusual neck pathology in a Nevisian prehistoric individual
    Datum 2007/01/01
    Sprache en
    Bibliothekskatalog www.academia.edu
    URL https://www.academia.edu/1400208/Unusual_neck_pathology_in_a_Nevisian_prehistoric_individual
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